Chronic migraines may be due to inflammation of neurons and cells in a part of the brain called the trigeminovascular system. A clinical trial investigated whether coQ10 supplements could reduce inflammation in 45 women with episodic migraines. The women took mg daily doses of either a CoQ10 supplement or a placebo. The women who took the CoQ10 supplements had fewer and less intense migraines when compared to the placebo group.
Women who took the CoQ10 supplements also showed lower levels of certain inflammatory biomarkers. Inflammatory biomarkers are substances in the blood that indicate the presence of inflammation somewhere in the body. A meta-analysis reexamined five studies investigating the use of CoQ10 supplements for migraines. The meta-analysis concluded that CoQ10 is more effective than a placebo at reducing the duration of migraines. However, CoQ10 did not appear to affect migraine severity or frequency.
These diseases are associated with free radical damage. A study investigated the effect of a Mediterranean diet combined with CoQ10 supplementation on metabolism in elderly adults. This combination led to an increase in antioxidant biomarkers in the urine. The authors concluded that taking CoQ10 and eating a diet low in saturated fat may help protect against diseases caused by free radical damage.
In another study , older adults received CoQ10 and selenium supplements for 48 months. The participants reported improvements in vitality, physical performance, and overall quality of life. CoQ10 supplements appear to be safe, and most people tolerate them even at high doses. However, CoQ10 supplements can cause the following side effects:.
People should consult a doctor before taking any new medications or dietary supplements, including CoQ CoQ10 is an antioxidant that exists in almost every cell of the human body. Although the body naturally produces CoQ10, some people may benefit from taking supplements. Overall, CoQ10 supplements appear relatively safe and cause few side effects. Supplements are not regulated by the Food and Drug Administration FDA for purity or verified for labeling accuracy, so purchase only those products that have been tested by an independent lab.
People who are interested in trying CoQ10 supplements may want to consult a healthcare professional first. Experts do not recommend CoQ10 for people taking blood-thinning medications, insulin , or certain chemotherapy drugs. CoQ10 is available in some drug stores, pharmacies, and online. We picked linked items based on the quality of products, and list the pros and cons of each to help you determine which will work best for you.
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Please try again. Mitochondria — often referred to as the powerhouses of cells — are specialized structures that produce adenosine triphosphate ATP , which is the main source of energy used by your cells 1. Ubiquinone is converted to its active form, ubiquinol, which is then readily absorbed and utilized by your body 2. Aside from being naturally produced by your body, CoQ10 can be obtained through foods including eggs, fatty fish , organ meats, nuts and poultry 3. CoQ10 plays a fundamental role in energy production and acts as a powerful antioxidant, inhibiting free radical generation and preventing cell damage 4.
Though your body makes CoQ10, several factors can deplete its levels. For example, the rate of its production significantly declines with age, which is associated with the onset of age-related conditions like heart disease and cognitive decline 5. Other causes of CoQ10 depletion include statin medication use, heart disease, nutrient deficiencies, genetic mutations, oxidative stress and cancer 6. Supplementing with CoQ10 has been shown to counteract damage or improve conditions related to a deficiency in this important compound.
CoQ10 is a compound with many important functions in your body. Various factors can deplete CoQ10 levels, which is why supplements may become necessary. Though 90— mg of CoQ10 per day is typically recommended, needs can vary depending on the person and condition being treated 8. Statins are a group of medications that are used to lower high blood levels of cholesterol or triglycerides to prevent heart disease 9.
Though these drugs are generally well tolerated, they can cause adverse side effects, such as serious muscle injury and liver damage. Statins also interfere with the production of mevalonic acid, which is used to form CoQ This has been shown to significantly decrease CoQ10 levels in the blood and muscle tissues Research has shown that supplementing with CoQ10 reduces muscle pain in those taking statin medications. However, other studies have shown no effect, emphasizing the need for more research on this topic For people taking statin medications, the typical dosage recommendation for CoQ10 is 30— mg per day Those with heart conditions, such as heart failure and angina, may benefit from taking a CoQ10 supplement.
A review of 13 studies in people with heart failure found that mg of CoQ10 per day for 12 weeks improved blood flow from the heart Plus, supplementing has been shown to reduce the number of hospital visits and the risk of dying from heart-related issues in individuals with heart failure CoQ10 is also effective in reducing the pain associated with angina, which is chest pain caused by your heart muscle not getting enough oxygen For people with heart failure or angina, the typical dosage recommendation for CoQ10 is 60— mg per day When used alone or in combination with other nutrients, such as magnesium and riboflavin, CoQ10 has been shown to improve migraine symptoms.
It has also been found to ease headaches by reducing oxidative stress and free radical production, which may otherwise trigger migraines. CoQ10 decreases inflammation in your body and improves mitochondrial function, which helps reduce migraine-associated pain A three-month study in 45 women demonstrated that those treated with mg of CoQ10 per day experienced significant reductions in the frequency, severity and duration of migraines, compared to a placebo group For treating migraines, the typical dosage recommendation for CoQ10 is — mg per day As mentioned above, CoQ10 levels naturally deplete with age.
Thankfully, supplements can raise your levels of CoQ10 and may even improve your overall quality of life.
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