In some men, a low sperm count is caused by a low testosterone level. It might seem logical to give more testosterone to a man with a low testosterone level; however, doing so can actually decrease his sperm count. A similar situation exists in women, as birth control pills with estrogen prevent egg development and ovulation. A clinical study at Texas Fertility Center found that Clomid caused a statistically significant increase in sperm concentration.
In some cases, the increase was so great that couples who initially had no alternative other than IVF were able to conceive with IUI instead. Instead of prescribing testosterone to treat male factor infertility, physicians will prescribe Clomid, the same drug that our Austin fertility specialists give to women to help them ovulate. Testosterone blood tests are usually completed in the morning as that is when testosterone levels are the highest. Clomid is prescribed at a much lower dosage for men than it is for women.
There is not a universally accepted recommended dosage for treating male fertility with Clomid, but usually, it is prescribed between 25 mg every other day and 50 mg daily. Be sure to speak with a fertility specialist or your healthcare provider regarding dosing, as high Clomid dosages can have a negative effect on sperm.
Sperm take between 90 to days to fully develop prior to being ejaculated. As such, it takes time to see the results of Clomid treatment on sperm quality. Therefore, men should take Clomid for as long as possible ideally months before trying to conceive naturally or with the assistance of fertility treatments.
Research has shown that Clomid is well tolerated for a majority of men and that it can help men reach normal testosterone levels and improve low T symptoms. Taking Clomid is just one of many ways men can improve their fertility. There are also several different fertility treatments available to overcome male fertility issues. In addition to oral medications, male infertility can also be treated via injectable medications like human chorionic gonadotropin hCG or human menopausal gonadotropin hMG.
Human Chorionic Gonadotropin hCG : hCG has been shown to help induce testis growth, improve spermatogenesis and increase fertility in gonadotrophin-deficient men. In combination, hCG and hMG have been shown to increase sperm count and motility. There are many supplements available to increase sperm quality and male fertility. Clomid can also reduce the amount and quality of your cervical mucus.
When exposed to estrogen, cervical mucus is thin and watery, which helps the sperm cells travel up to the fallopian tubes. When taking Clomid, estrogen levels are lower, causing the cervical mucus to be thicker than usual. This can interfere with the ability of the sperm to get into the uterus and fallopian tubes.
So far, there is no conclusive data that Clomid increases cancer risk in women. But there is some research suggesting a possible increase in endometrial cancer with the use of ovulation-inducing agents.
To date, the research has not shown a significant risk for miscarriage, birth defects, or other pregnancy complications. You should speak with your doctor about any specific concerns. It may just mean that you need a different form of treatment or that something additional is going on.
Your doctor will likely suggest additional testing to identify these issues so they can be corrected before future treatment cycles. This process results from a complicated series of hormonal changes that occur in the beginning of her cycle. This egg then travels down the fallopian tube where it may or may not be fertilized by a sperm cell.
If the egg is fertilized, it may implant in the uterine lining and cause a pregnancy. Without regular ovulation, it can become difficult to get pregnant. The odds of a woman getting pregnant by having sex while on her period are low, but not zero. The U. Food and Drug Administration FDA approved this oral fertility medication for use in women who are unable to become pregnant. It affects the hormone balance within the body and promotes ovulation.
The FDA approved Clomid only for use in women. Learn more about off-label prescription drug use. Clomid blocks the hormone estrogen from interacting with the pituitary gland. When estrogen interacts with the pituitary gland, less luteinizing hormone LH and follicle-stimulating hormone FSH are produced. This leads to a decrease in testosterone and therefore decreased sperm production.
The dose given can range from A recent review recommends a starting dosage of 25 mg three days per week and then slowly titrating — or adjusting the dosage — until the dose is 50 mg per day as needed. High doses of Clomid can actually have a negative effect on sperm count and motility. Always work with your healthcare provider to ensure proper dosage. Clomid is prescribed off-label for male infertility, particularly where low testosterone levels are observed.
According to the Centers for Disease Control and Prevention , both a male and a female factor are identified in 35 percent of couples who encounter challenges trying to conceive. In 8 percent of couples, only a male factor is identified. There are few controlled studies of Clomid use in males. However, possible side effects due to induced hormonal changes include:.
The side effects of Clomid are typically reversible after stopping the medication. If any of the side effects listed above occur while taking Clomid, discontinue taking Clomid and seek medical treatment. A recent review of Clomid use in male infertility cases found mixed results regarding efficacy, or effectiveness.
Some of the studies reviewed demonstrated a moderate improvement in sperm count in males with low sperm count or unexplained infertility.
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